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<channel>
	<title>Esemplastic thermoplastic &#187; science</title>
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	<description>chemists are reactive scientists</description>
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		<title>science in review: june 2010</title>
		<link>http://drzubkov.com/2010/07/science-in-review-june-2010/</link>
		<comments>http://drzubkov.com/2010/07/science-in-review-june-2010/#comments</comments>
		<pubDate>Tue, 06 Jul 2010 20:21:17 +0000</pubDate>
		<dc:creator>cubbi</dc:creator>
				<category><![CDATA[science]]></category>

		<guid isPermaLink="false">http://drzubkov.com/?p=1020</guid>
		<description><![CDATA[Another bit of science fiction became reality last month as the first solar sail was unfurled on june 3rd, 2010, by the japanese spacecraft on its way to Venus. Also in really impressive news, artificial nanoparticle antibody, made of plastic, was tested in vivo, and worked. It was imprinted with sensitivity to bee venom, injected [...]]]></description>
			<content:encoded><![CDATA[<p>Another bit of science fiction became reality last month as <a href="http://www.jaxa.jp/press/2010/06/20100611_ikaros_e.html">the first solar sail was unfurled</a> on june 3rd, 2010, by the japanese spacecraft on its way to Venus.</p>
<p>Also in really impressive news, <a href="http://pubs.acs.org/doi/abs/10.1021/ja102148f">artificial nanoparticle antibody</a>, made of plastic, was tested <i>in vivo</i>, and worked. It was imprinted with sensitivity to bee venom, injected into bloodstream of mice who were given lethal injections of the venom, and it saved them. I have to admit, nanoscience is getting exciting.</p>
<p>Speaking of hot topics, graphene was in several publications, one of which showed <a href="http://www.nature.com/nnano/journal/vaop/ncurrent/abs/nnano.2010.132.html">how to make 30-inch sheets of it</a>, big enough for LCDs and touchscreens. (It is better than the common indium tin oxide, especially in terms of flexibility and price)</p>
<p>Physics had a lot of interesting stuff going on: tau-neutrino oscillated from mu-neutrinos shot from CERN <a href="http://cdsweb.cern.ch/record/1269064">was directly observed</a>.</p>
<p>Photoemission <a href="http://www.sciencemag.org/cgi/content/abstract/328/5986/1658">was shown to be not instant</a>: it takes an extra 21 attoseconds to kick an electron off a 2p orbital compared to the 2s orbital of a neon atom. Which is also the new record for the shortest directly measured time interval.</p>
<p>The australians who already stopped light for a second, are further improving their <a href="http://www.nature.com/nature/journal/v465/n7301/full/nature09081.html">quantum memory for light</a>, promising hours soon.</p>
<p>A curious student earned himself a first-name article in Nature and a PhD by building <a href="http://www.nature.com/nature/journal/v465/n7299/full/nature09069.html">a theory of bubble bursting</a>, which explains how surface bubble break-up happens and why is there sometimes a ring of smaller daughter bubbles created.</p>
<p>Another experiment you can do yourself: stretch a dribble of spit between two fingers and little beads on a string will form. <a href="http://www.nature.com/nphys/journal/vaop/ncurrent/abs/nphys1682.html"> A theory to explain them</a> was just published in Nature as well (it&#8217;s not as useless as you&#8217;d think, it explains similar beads in inkjet printers, in the industrial processes involving polymer solutions, etc)</p>
<p>Yet another curious student created a <a href="http://prl.aps.org/abstract/PRL/v104/i24/e248001">brownian motion motor</a>, imagined in 1912 and proved impossible (in equilibrium gas) by Feynman in 1963.</p>
<p>In more bizarre physics, a <a href="http://www.opticsinfobase.org/abstract.cfm?URI=oe-18-13-13385">&#8220;dark pulse laser&#8221;</a> was built, a quantum dot laser producing impulses of.. dark.</p>
<p>Not as much jumped at me in biology news, but the antibiotic property of honey, known for thousands of years, <a href="http://dx.doi.org/10.1096/fj.09-150789">was finally identified</a> &#8211; it&#8217;s a protein called defensin-1, a part of the honey bee immune system (aided by sugar, hydrogen peroxide, and methylglyoxal). And the four-leaf clover <a href="http://crop.scijournals.org/cgi/content/abstract/50/4/1260">gene was identified</a> so we can genetically engineer luck.</p>
<p>In unfortunate news, The AIDS denialists rejoice as the investigation into misconduct of their crazy leader Peter Duesberg concluded with &#8220;insufficient evidence&#8221;. (After <a href="http://journals.lww.com/jaids/pages/articleviewer.aspx?year=2008&#038;issue=12010&#038;article=00010&#038;type=abstract">over 330,000 deaths were attributed to his health policies</a> in South Africa, he responded with the <a href="http://www.ncbi.nlm.nih.gov/pubmed/19619953">now withdrawn article</a> in 2009 which was so bad it prompted the investigation, but Berkley closed it last month saying &#8220;The university relies on the scholarly peer-review process, rather than disciplinary procedures, for evaluating the value of scientific work&#8221;)</p>
<p>In an astronomical disappointment, the rings around Saturn&#8217;s moon Rhea, <a href="http://www.sciencemag.org/cgi/content/abstract/sci;319/5868/1380">announced in 2008</a> were <a href="http://news.sciencemag.org/sciencenow/2010/06/the-moon-rings-that-never-were.html">ruled out</a>.</p>
<p>And, just for the sake of the cool title, I have to quote the <a href="http://www.agu.org/pubs/crossref/2010/2009JA014508.shtml">video recordings of sprites and elves</a>.</p>
<p><small>Crossposted from<a href="http://cubbi.livejournal.com/77501.html">LiveJournal</a></small></p>
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		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>C++0x in Continuation-passing Style</title>
		<link>http://drzubkov.com/2010/06/c0x-in-continuation-passing-style/</link>
		<comments>http://drzubkov.com/2010/06/c0x-in-continuation-passing-style/#comments</comments>
		<pubDate>Fri, 11 Jun 2010 04:35:22 +0000</pubDate>
		<dc:creator>cubbi</dc:creator>
				<category><![CDATA[computer science]]></category>

		<guid isPermaLink="false">http://drzubkov.com/?p=1018</guid>
		<description><![CDATA[Continuation-passing style (wiki) is a theoretical concept from functional programming that Scheme came up with in 1975. Well now that it&#8217;s 2010 and functions are first-class citizens of the C++ universe, too, along with closures. So I figured.. can I write CPS in C++? Yes, I can! We can have functional programming now! Here&#8217;s Scheme [...]]]></description>
			<content:encoded><![CDATA[<p>Continuation-passing style (<a href="http://en.wikipedia.org/wiki/Continuation-passing_style">wiki</a>) is a theoretical concept from functional programming that Scheme came up with in 1975. Well now that it&#8217;s 2010 and functions are first-class citizens of the C++ universe, too, along with closures. So I figured.. can I write CPS in C++? Yes, I can! We can have functional programming now!</p>
<p>Here&#8217;s Scheme example from the wiki:</p>
<pre>
(define (factorial n k)
 (cps= n 0 (lambda (b)
   (cps-if b
     (k 1)
     (cps- n 1 (lambda (nm1)
       (factorial nm1 (lambda (f)
         (cps* n f k)))))))))
</pre>
<p>And here&#8217;s what I made with C++</p>
<pre>
void factorial(int n, function&lt;void (int)&gt; k) {
 cps2(equal_to&lt;int&gt;(), 0, n,
  [&#038;](bool b){cps_ifthen(b,
   [&#038;](){k(1);},
   [&#038;](){cps2(minus&lt;int&gt;(), n, 1,
    [&#038;](int nm1){factorial(nm1,
     [&#038;](int f){cps2(multiplies&lt;int&gt;(), n, f, k);});});});});
}
</pre>
<p>To compile the function above, I had to define a couple CPS primitives, of course, just like in Scheme:</p>
<pre>
#include &lt;iostream&gt;
#include &lt;functional&gt;
#include &lt;cmath&gt;
using namespace std;

template&lt;typename F, typename A, typename K&gt;
void cps1(F f, A a, K k) { k(f(a)); }
template&lt;typename F, typename A1, typename A2, typename K&gt;
void cps2(F f, A1 a1, A2 a2, K k) { k(f(a1, a2)); }
template&lt;typename F1, typename F2&gt;
void cps_ifthen(bool x, F1 k1, F2 k2) {x ? k1() : k2();}

void factorial(int n, function&lt;void (int)&gt; k)
{
    cps2(equal_to&lt;int&gt;(), 0, n,
        [&#038;](bool b){cps_ifthen(b,
            [&#038;](){k(1);},
            [&#038;](){cps2(minus&lt;int&gt;(), n, 1,
                [&#038;](int nm1){factorial(nm1,
                    [&#038;](int f){cps2(multiplies&lt;int&gt;(), n, f, k);});});});});
}
int main()
{
    for(int i=0; i<10; ++i) {
        cout &lt;&lt; "F("&lt;&lt;i&lt;&lt;"): " &lt;&lt; tgamma(i+1) &lt;&lt; " or ";
        factorial(i, [](int a) {cout &lt;&lt; a &lt;&lt; '\n';});
    }
}
</pre>
<p>test run:</p>
<pre>
cubbi@gummadoon ~ $ g++ -std=c++0x -pedantic -Wall -Wextra -o cps cps.cc
cubbi@gummadoon ~ $ ./cps
F(0): 1 or 1
F(1): 1 or 1
F(2): 2 or 2
F(3): 6 or 6
F(4): 24 or 24
F(5): 120 or 120
F(6): 720 or 720
F(7): 5040 or 5040
F(8): 40320 or 40320
F(9): 362880 or 362880
</pre>
<p>I could simplify cps1 and cps2 into a variadic version</p>
<pre>
template&lt;typename K, typename F, typename... A&gt;
void cps(K k, F f, A... a) { k(f(a...)); }
</pre>
<p>but then the order of arguments would make it look too different for neat juxtaposition, since variadic parameter pack must be in the end of the argument list.</p>
<p><small>Crossposted from <A href="http://cubbi.livejournal.com/76596.html">Livejournal</a></small></p>
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		<slash:comments>1</slash:comments>
		</item>
		<item>
		<title>May 2010 in science</title>
		<link>http://drzubkov.com/2010/06/may-2010-in-science/</link>
		<comments>http://drzubkov.com/2010/06/may-2010-in-science/#comments</comments>
		<pubDate>Fri, 04 Jun 2010 05:54:43 +0000</pubDate>
		<dc:creator>cubbi</dc:creator>
				<category><![CDATA[biology]]></category>
		<category><![CDATA[science]]></category>

		<guid isPermaLink="false">http://drzubkov.com/?p=1014</guid>
		<description><![CDATA[The biggest news was of course &#8220;Scientists Create Life!!!&#8221; &#8212; the group that has been tediously working on Mycoplasma which, back when they began, was known as the bacterium with the smallest genome (now we know about Pelagibacter ubique, which is so much more awesome in many ways) finally did it, they fully synthesized its [...]]]></description>
			<content:encoded><![CDATA[<p>The biggest news was of course &#8220;Scientists Create Life!!!&#8221; &#8212; the group that has been tediously working on Mycoplasma which, back when they began, was known as the bacterium with the smallest genome (now we know about <a href="http://en.wikipedia.org/wiki/Pelagibacter%20ubique">Pelagibacter ubique</a>, which is so much more awesome in many ways) finally did it, they <a href="http://dx.doi.org/10.1126/science.1190719">fully synthesized its entire genome</a> from scratch, with some modifications, and &#8220;booted&#8221; it in a different bacteria which then died to produce their new cell.</p>
<p>In a do-over after their <a href="http://dx.doi.org/10.1038/nature05336">2006 failure</a>, Neanderthal genome <a href="http://dx.doi.org/10.1126/science.1188021">was finally sequenced</a> (60% of it) and confirmed that it wasn&#8217;t all war when modern humans left Africa, there was some interbreeding going on too, which made us all 1% &#8211; 4% Neanderthal. Although the important implications were the identification of the 78 genes that separate us &#8211; most of them already known as genes that deal with human brain because mutations in them cause everything from Down&#8217;s (DYRK1A) to Autism disorders (CADPS2 and AUTS2). Too bad we&#8217;re not allowed to mod a human germ cell and grow up a Neanderthal child in a test tube.</p>
<p>In another example of prehistoric genetics, a wooly mammoth gene was inserted in E.coli to express mammoth hemoglobin and to study how does it work at low temperatures. I just love how the first sentence of the article&#8217;s abstract says <a href="http://www.nature.com/ng/journal/v42/n6/abs/ng.574.html">&#8220;We have successfully resurrected &#8230;&#8221;</a></p>
<p>To the joy of quacks everywhere, acupuncture was meticulously studied and <a href="http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.2562.html">proven to relieve pain in mice</a> (as long as the mice don&#8217;t have the mutation that removes their adenosine receptors). Of course you don&#8217;t have to know anything about magical energies, it&#8217;s the tissue damage that releases the pain-killing chemical.</p>
<p>Speaking of researching the antiscientific, a three year long study showed that both lab and wild birds <a href="http://www3.interscience.wiley.com/journal/123446916/abstract">prefer conventionally-grown grain to &#8220;organic&#8221; grain</a> because of its higher nutritional content (but it takes them a while to learn the difference). Not a surprise to me, I never buy &#8220;organic&#8221; food myself anyway, but the authors just had to say they are overturning a &#8220;dogma&#8221;.</p>
<p>Oh and while I&#8217;m on quakery subject, Wakefield&#8217;s old papers about his made-up vaccination-autism connection <a href="http://www.nature.com/ajg/journal/v105/n5/full/ajg2010149a.html">were retracted from public record</a> by The Lancet and American Journal of Gastroenterology &#8212; about time!</p>
<p>Since it&#8217;s all about biology today, a couple biologists from New Hampshire played <strike>God</strike> Nature by changing whole-island populations of predators and lizards on six tiny Caribbean islands and <a href="http://dx.doi.org/10.1038/nature09020">evolved some tough anole lizards</a> in a field experiment on natural selection. </p>
<p>Also, apparently we can now reprogram the poor abused E.coli <a href="http://www.nature.com/nchembio/journal/v6/n6/abs/nchembio.369.html">to seek and destroy specific chemicals</a>, in this case, a herbicide.</p>
<p>And for a quick round-up of the bizarre, <a href="http://www.nature.com/news/2005/050131/full/news050131-5.html">Monkeys pay for porn</a>,  2-toed sloths <a href="http://dx.doi.org/10.1016%2Fj.mambio.2010.03.003">hide in outhouses to eat our poop</a>, and there&#8217;s a <a href="http://dotearth.blogs.nytimes.com/2010/05/31/dot-shot-sinkhole-in-guatemala-city/">new gaping hole in the middle of Guatemala city</a>.</p>
<p>That&#8217;s it for May. Enjoy the <a href="http://illusioncontest.neuralcorrelate.com/2010/impossible-motion-magnet-like-slopes/">World&#8217;s Best Visual Illusion</a> of 2010!</p>
]]></content:encoded>
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		</item>
		<item>
		<title>April in science!</title>
		<link>http://drzubkov.com/2010/05/april-in-science/</link>
		<comments>http://drzubkov.com/2010/05/april-in-science/#comments</comments>
		<pubDate>Tue, 04 May 2010 19:39:04 +0000</pubDate>
		<dc:creator>cubbi</dc:creator>
				<category><![CDATA[science]]></category>

		<guid isPermaLink="false">http://drzubkov.com/?p=1011</guid>
		<description><![CDATA[So what happened besides the eruption of Eyjafjallajökull, the oil spill, and the return of the deadly virulent fungus from Vancouver Island? Element 117 was created, 8 years after the heavier 118. It took a year to scrape up 22 mg of Bk in Oak Ridge and 5 months of bombarding it with Ca in [...]]]></description>
			<content:encoded><![CDATA[<p>So what happened besides the eruption of Eyjafjallajökull, the oil spill, and the return of the <a href="http://news.sciencemag.org/sciencenow/2010/04/new-concerns-about-deadly-fungus.html">deadly virulent fungus</a> from Vancouver Island?</p>
<p><a href="http://prl.aps.org/abstract/PRL/v104/i14/e142502">Element 117 was created</a>, 8 years after the heavier 118. It took a year to scrape up 22 mg of Bk in Oak Ridge and 5 months of bombarding it with Ca in Dubna to generate 6 atoms. The cool thing is that it confirms that neutron-rich superheavy elements are more stable, and Island of Stability may not be stuff of fiction after all.</p>
<p>Speaking of fiction, some guys showed off their ability to solve the inverse problem of electromagnetism by designing, fabricating, and characterizing a <a href="http://www.sciencemag.org/cgi/content/abstract/328/5976/337">3D invisibility-cloaking device</a> (no, it&#8217;s not big enough for a human.. yet?).</p>
<p>Another stuff of fiction turning real: a <a href="http://www.nature.com/nphys/journal/v6/n5/abs/nphys1636.html">self-healing organic molecular monolayer</a> was made that worked like a massively parallel computer, solving a variety of computational tasks. This is kinda exciting.</p>
<p>In astronomy, the origin of zodiacal light, long taught to be dust from colliding asteroids, was shown to have come from <a href="http://iopscience.iop.org/0004-637X/713/2/816">disintegrating comets instead<a> (much to rejoicing of <a href="http://en.wikipedia.org/wiki/Bill_Napier">Bill Napier</a>).</p>
<p>Also, water and organic molecules are <a href="http://www.nature.com/nature/journal/v464/n7293/abs/nature09029.html#/">not just present, but *prevalent*</a> on the surface of one asteroid, 24 Thermis.</p>
<p>Oh, and LRO <a href="http://www.sciencedaily.com/releases/2010/04/100426203545.htm">found the first Soviet Moon rover</a>, Lunokhod-1, with perfectly functioning reflector, to everybody&#8217;s surprise.</p>
<p>After those physics news, chemistry looks dull with its <a href="http://www.sciencemag.org/cgi/content/abstract/328/5976/339">aromatic carbon-lead compound</a> and <a href="http://www.sciencemag.org/cgi/content/abstract/328/5976/345">triple bond between boron and oxygen</a> (or maybe I didn&#8217;t have the time to read more journals)</p>
<p>Biology had more cool news, though, the first multicellular organism was found that lives <a href="http://www.biomedcentral.com/1741-7007/8/30/abstract">entirely without oxygen</a>. They have hydrogenosomes instead of mitochondria. (oh, hey, it is <a href="http://en.wikipedia.org/wiki/Loricifera">on wikipedia already<a/>)</p>
<p>Also the <a href="http://www.sciencemag.org/cgi/content/summary/328/5978/574">first animal to produce carotenoids</a> was found, a red aphid, which picked up necessary genes from some fungus a long time ago.</p>
<p>Speaking of picking up genes, <a href="http://www.nature.com/nature/journal/v464/n7293/full/nature08939.html">blood-sucking parasites exchange DNA</a> (namely, transposons) with mammals. One bug, triatomine, has DNA of opossums and monkeys, and another of another bunch of mammals. Talk about lateral gene transfer!</p>
<p>Wasn&#8217;t even so much bizarre in biology news.. maybe those caterpillars that <a href="http://www.nature.com/ncomms/journal/v1/n1/abs/ncomms1002.html#/">talk with their butts</a>, or these male spiders, who are usually eaten by their partners after mating, but when<br />
one realizes he&#8217;s mating his own sister, he <a href="http://rsbl.royalsocietypublishing.org/content/early/2010/04/13/rsbl.2010.0214.abstract">pulls out before finishing</a>.</p>
<p><small>Crossposted from <a href="http://cubbi.livejournal.com/75620.html">LiveJournal</a></small></p>
]]></content:encoded>
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		</item>
		<item>
		<title>March in science!</title>
		<link>http://drzubkov.com/2010/04/march-in-science/</link>
		<comments>http://drzubkov.com/2010/04/march-in-science/#comments</comments>
		<pubDate>Wed, 14 Apr 2010 16:17:30 +0000</pubDate>
		<dc:creator>cubbi</dc:creator>
				<category><![CDATA[science]]></category>

		<guid isPermaLink="false">http://drzubkov.com/?p=1003</guid>
		<description><![CDATA[Wow I am two weeks late, between business trips and FCN (which was awesome, despite the long drive to the chilly Detroit) Still no time to page through JACS or PNAS, so just the big news items and a couple oddities: The 4th natural mechanism of oxygen production was discovered (did you think photosynthesis was [...]]]></description>
			<content:encoded><![CDATA[<p>Wow I am two weeks late, between business trips and FCN (which was awesome, despite the long drive to the chilly Detroit)<br />
Still no time to page through JACS or PNAS, so just the big news items and a couple oddities:</p>
<p>The 4th natural mechanism of <a href="http://www.nature.com/nature/journal/v464/n7288/full/nature08883.html">oxygen production was discovered</a> (did you think photosynthesis was the only one?).</p>
<p>The pungent smell of wasabi, mustard, garlic, or acrolein is the oldest sense we have, <a href="http://www.nature.com/nature/journal/v464/n7288/full/nature08848.html">our common ancestor with insects had it</a>, 500 million years ago.</p>
<p>We finally know why do people die from SIRS after severe trauma (SIRS is just like sepsis, but without infection) &#8211; apparently our own <a href="http://www.nature.com/nature/journal/v464/n7285/full/nature08780.html">mitochondria still look enough like dangerous bacteria</a> when they enter blood stream <i>en masse</i> from the damaged tissue, and our immune system goes into overdrive. So now doctors can treat it, as long as they are really sure there is no infection.</p>
<p>Sex differentiation for birds (namely, chicken) was found to be cell-autonomous. Meaning, unlike humans, where embrios are sexless until 7 weeks old and tissues can change under hormone therapy, <a href="http://www.nature.com/nature/journal/v464/n7286/full/nature08852.html">every cell of a chicken is male or female from the start</a> (or from about 18 hours after fertilization). And to study that, they had to find three bizarre hermaphroditic chickens where half of the body was male and half was female.</p>
<p>DNA analysis of a 40k year old finger from Siberia found <a href="http://www.nature.com/nature/journal/vaop/ncurrent/abs/nature08976.html"> the fourth line of ancient humans</a>, besides modern, neanderthal, and the &#8220;hobbits&#8221; from Flores, who all lived only that recently, having diverged over a million years ago.</p>
<p>Male pipefish (a kind of seahorse), who become pregnant from their female partners, can, it turns out, <a href="http://www.nature.com/nature/journal/v464/n7287/full/nature08861.html"> selectively abort the embryos from unattractive mothers</a>, talk about pro choice!</p>
<p><a href="http://journals.cambridge.org/action/displayAbstract?fromPage=online&#038;aid=7311680">The sixth taste was probably discovered</a> in humans &#8211; in addition to sweet, salt, sour, bitter, and umami, some humans were shown to taste fat, and those who can taste it really well, eat less of it, too.</p>
<p>For non-biological news, the &#8220;Exceptionally Simple Theory of Everything&#8221; based on the awesome 248-dimensional <a href="http://en.wikipedia.org/wiki/E8_(mathematics)">Exceptionally Simple Lie group E8</a>, was <a href="http://springerlink.com/content/h3h4wh813606ggq8/?p=5938e95db2ea40938025d7dd6b7d08df&#038;pi=0">conclusively dismantled</a>.</p>
<p>Good old <a href="http://www.nature.com/nature/journal/v464/n7286/full/nature08857.html">General Relativity was confirmed</a> to hold true for at least as far as 3.5 billion light years from Earth by a survey of 70,000 galaxies, which also disproved one of the alternative theories, <a href="http://en.wikipedia.org/wiki/TeVeS">TeVeS</a>, and left another competing theory, <a href="http://en.wikipedia.org/wiki/F(R)_gravity">f(R)</a>, without a distinct ruling. They want to survey a million galaxies when BOSS is done in 5 years to narrow down the expirimental errors.</p>
<p>And, finally, to the amusement of astronomers, thermal map of one of Saturn&#8217;s moons looks like a giant <a href="http://news.sciencemag.org/sciencenow/2010/03/scienceshot-pac-man-gobbles-the-.html">Pac-Man eating the Death Star</a>.</p>
<p><small>Crossposted from <a href="http://cubbi.livejournal.com/75259.html">LiveJournal</a></small></p>
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		<title>Things I won&#8217;t work with, either</title>
		<link>http://drzubkov.com/2010/03/things-i-wont-work-with-either/</link>
		<comments>http://drzubkov.com/2010/03/things-i-wont-work-with-either/#comments</comments>
		<pubDate>Fri, 05 Mar 2010 23:01:19 +0000</pubDate>
		<dc:creator>cubbi</dc:creator>
				<category><![CDATA[chemistry]]></category>

		<guid isPermaLink="false">http://drzubkov.com/?p=997</guid>
		<description><![CDATA[I was randomly linked to an awesome blog of an organic chemist who wrote, among other things, several posts titled &#8220;Things I won&#8217;t work with&#8221;. Here: http://pipeline.corante.com/archives/things_i_wont_work_with/ Even if you&#8217;re a non-chemist, you will appreciate the compounds that can force evacuation of a village when their scent wafts over from an open flask in a [...]]]></description>
			<content:encoded><![CDATA[<p>I was randomly linked to an awesome blog of an organic chemist who wrote, among other things, several posts titled &#8220;Things I won&#8217;t work with&#8221;. Here: http://pipeline.corante.com/archives/things_i_wont_work_with/</p>
<p>Even if you&#8217;re a non-chemist, you will appreciate the compounds that can force evacuation of a village when their scent wafts over from an open flask in a nearby college, compounds that set concrete, sand, bricks, water, and people on fire as they happily burn through them, or compounds that just blow up while standing undisturbed in the dark at cryogenic temperatures.</p>
<p>Fun stuff.. And no, I didn&#8217;t work with any of the title compounds either <img src='http://drzubkov.com/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' /> </p>
<p><small>Crossposted from <a href="http://cubbi.livejournal.com/74167.html">Livejournal</a></small></p>
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		<title>february 2010 in science</title>
		<link>http://drzubkov.com/2010/03/february-2010-in-science/</link>
		<comments>http://drzubkov.com/2010/03/february-2010-in-science/#comments</comments>
		<pubDate>Mon, 01 Mar 2010 17:08:05 +0000</pubDate>
		<dc:creator>cubbi</dc:creator>
				<category><![CDATA[science]]></category>

		<guid isPermaLink="false">http://drzubkov.com/?p=994</guid>
		<description><![CDATA[So, this is what february 2010 added to the collective knowledge of humankind: Chemistry A 1 GHz NMR spectrometer (that&#8217;s 23.5 Tesla) was brought online in Lyon, the new long-awaited record after Bruker 950 MHz spectrometers appeared in 2006. It costed over 11 million euros, so don&#8217;t expect your college getting one soon. Speaking of [...]]]></description>
			<content:encoded><![CDATA[<p>So, this is what february 2010 added to the collective knowledge of humankind:</p>
<p><i>Chemistry</i><br />
A <a href="http://www.nature.com/news/2010/100203/full/463605a.html">1 GHz NMR spectrometer</a> (that&#8217;s 23.5 Tesla) was brought online in Lyon, the new long-awaited record after Bruker 950 MHz spectrometers appeared in 2006. It costed over 11 million euros, so don&#8217;t expect your college getting one soon. Speaking of NMR, the largest ever distance between two nuclei, 14.4 A, was measured <a href="http://pubs.acs.org/doi/abs/10.1021/ja908915v">with tritium-labeled MAS NMR</a> (normally, your regular biochemical 1H liquid state NOE NMR measures only up to 6 A).</p>
<p>Also in chemistry, where dozens of new reactions are developed every month, two remarkably simple ones were made in February: a <a href="http://pubs.acs.org/doi/abs/10.1021/ja910083q">zinc-catalized reduction of amides</a> to amines which tolerates alkyl, aryl, heterocyclic, esters, ethers, nitro, cyano, azo, and keto substituents, touching nothing but amides. The other one is a one-pot <a href="http://pubs.acs.org/doi/abs/10.1021/ja910503k">synthesis of 1,3-disubstituted allenes</a> from a 1-alkyne and an aldehyde.</p>
<p>By the way, someone finally made <a href="http://pubs.acs.org/doi/abs/10.1021/ja909614x">a fullerenium salt, C60(AsF6)2</a>, and it turned out to be a regular semiconductor instead of the speculated high-temperature superconductor.</p>
<p>Also someone ambitiously claims to <a href="http://pubs.acs.org/doi/abs/10.1021/ja9101826">redefine the textbook definition of H3O+</a> in water, based on IR, but I don&#8217;t see how this agrees with <a href="http://www.pnas.org/content/102/40/14171">the 2005 fast scale study</a> and a host of others.</p>
<p>A superheavy isotope of carbon, carbon-22, <a href="http://link.aps.org/doi/10.1103/PhysRevLett.104.062701">was found to be more stable than expected</a>, and very hard to analyze with current theory. And finally, the element 112, produced back in 1996, was <a href="http://www.gsi.de/portrait/Pressemeldungen/19022010.html">finally given the official name Copernicium</a>, and chemical symbol Cn by IUPAC. Update your periodic tables!</p>
<p><i>Physics</i><br />
While LHC&#8217;s full run is getting <a href="http://www.sciencemag.org/cgi/content/full/327/5967/766">delayed until 2013</a>, RHIC (our own, Long Island based black hole generating doomsday device) is <a href="http://www.nature.com/news/2010/100216/full/news.2010.76.html">proving it can still do cool stuff</a> &#8212; analysis of 200 GeV quark-gluon plasma gave new hypotheses for barionic asymmetry and the large magnetic fields of the galaxies.</p>
<p>Also in the world of physics, a saser (a laser analog emitting sound waves) was finally made, in two different ways, by two groups simultaneously: in <a href="http://link.aps.org/doi/10.1103/PhysRevLett.104.083901">California</a> and <a href="http://link.aps.org/doi/10.1103/PhysRevLett.104.085501">UK</a>. Very cool things, hopefuly they&#8217;ll find use for them.</p>
<p>Another hardcore physics study, the crossover from BCS superfluid (weakly interacting pairs of fermions) to BEC supefluid (tightly bound bosonic molecules made of fermions) was studied with anticipation of something new and cool but was found to be <a href="http://www.nature.com/nature/journal/v463/n7284/full/nature08814.html">boring fermi fluid</a>.</p>
<p>And more physics: the 100 year old <a href="http://en.wikipedia.org/wiki/Abraham%E2%80%93Minkowski_controversy">Abraham-Minkowski dilemma</a> about the momentum of light was finally solved: <a href="http://link.aps.org/doi/10.1103/PhysRevLett.104.070401">both are correct</a>.</p>
<p><i>Biology</i><br />
A new oldest life form on Earth was <a href="http://www.nature.com/nature/journal/v463/n7283/full/nature08793.html">found and dated</a> to 3.2 billion years ago.</p>
<p>Yet another psychology research in the origin of religion shows that <a href="http://www.cell.com/trends/cognitive-sciences/abstract/S1364-6613(09)00289-7">moral judgments are not related to religious background</a>. At the same time, neuroscientists noticed that when they remove a chunk of rt. inf. parietal cortex (normally providing spatial awareness), patients <a href="http://www.cell.com/neuron/abstract/S0896-6273(10)00052-8">gain self-transcendence</a>.</p>
<p>Speaking of neurophysiology, although the &#8220;facilitated communication&#8221; for that belgian in persistent vegetative state <a href="http://www.guardian.co.uk/world/2010/feb/19/miracle-patient-facilitated-communication">turned out to be a hoax</a> (as anyone familiar with the idea should have known), a group of researchers who used fMRI in 2006 to get answers from a vegetative patient scanned 53 more and found that four of them also have <a href="http://news.sciencemag.org/sciencenow/2010/02/03-02.html">distinct brain activity patterns</a> in response to questions.</p>
<p>And, for something weird, <a href="http://jeb.biologists.org/cgi/content/full/213/4/i">bees can recognize human faces</a>.</p>
<p><small>Crossposted from <a href="http://cubbi.livejournal.com/73843.html">Livejournal</a></p>
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		<title>DSM-V</title>
		<link>http://drzubkov.com/2010/02/dsm-v/</link>
		<comments>http://drzubkov.com/2010/02/dsm-v/#comments</comments>
		<pubDate>Thu, 18 Feb 2010 11:43:17 +0000</pubDate>
		<dc:creator>cubbi</dc:creator>
				<category><![CDATA[medicine]]></category>

		<guid isPermaLink="false">http://drzubkov.com/?p=992</guid>
		<description><![CDATA[Oh, hey, temper tantrums, Restless Leg, binge eating, and cybersex addiction and other excessive sexual activity, are gonna be mental disorder in the USA now. Good thing Internet addiction didn&#8217;t make the cut due to insufficient evidence Crossposted from LiveJournal]]></description>
			<content:encoded><![CDATA[<p>Oh, hey, <a href="http://www.dsm5.org/ProposedRevisions/Pages/proposedrevision.aspx?rid=397">temper tantrums</a>, <a href="http://www.dsm5.org/ProposedRevisions/Pages/proposedrevision.aspx?rid=403">Restless Leg</a>, <a href="http://www.dsm5.org/ProposedRevisions/Pages/proposedrevision.aspx?rid=372">binge eating</a>, and <a href="http://www.dsm5.org/ProposedRevisions/Pages/proposedrevision.aspx?rid=415">cybersex addiction and other excessive sexual activity</a>, are gonna be mental disorder in the USA now. Good thing Internet addiction didn&#8217;t make the cut due to insufficient evidence <img src='http://drzubkov.com/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' /> </p>
<p><small>Crossposted from <a href="http://cubbi.livejournal.com/72954.html">LiveJournal</a></small></p>
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		<title>science review for january 2010</title>
		<link>http://drzubkov.com/2010/02/science-review-for-january-2010/</link>
		<comments>http://drzubkov.com/2010/02/science-review-for-january-2010/#comments</comments>
		<pubDate>Sat, 06 Feb 2010 14:00:48 +0000</pubDate>
		<dc:creator>cubbi</dc:creator>
				<category><![CDATA[science]]></category>

		<guid isPermaLink="false">http://drzubkov.com/?p=989</guid>
		<description><![CDATA[Running a little late here because I spent this week in the humid warmth of McAllen, TX, and I probably miss a few cool things.. but anyway: in chemistry news, An isomer of hexasilabenze was created, Si6R6, which turned out to be tricyclic (and bright green). It apparently is aromatic in some loose sense, and [...]]]></description>
			<content:encoded><![CDATA[<p>Running a little late here because I spent this week in the humid warmth of McAllen, TX, and I probably miss a few cool things.. but anyway:</p>
<p>in chemistry news, An isomer of <a<br />
href="http://www.sciencemag.org/cgi/content/abstract/327/5965/564">hexasilabenze was created</a>, Si6R6, which turned out to be tricyclic (and bright green). It apparently is aromatic in some loose sense, and the authors want to call this &#8216;dismutational aromaticity&#8217;. Before this, only hexasilaprismane has been made, of all the Si6R6 isomers, and it was definitely not aromatic. Also, a quantum computing team <a href="http://www.nature.com/nchem/journal/v2/n2/abs/nchem.483.html">calculated energy levels</a> of hydrogen molecule to 20 bit precision using photonic quantum computer. Would be nice to be able to do quantum chemisty calculations on large molecules one day.</p>
<p>in physics, the 80-year old bizarre prediction of Dirac&#8217;s relativistic QM theory called &#8220;Zitterbewegung&#8221; <a href="http://www.nature.com/doifinder/10.1038/nature08688">was tentatively confirmed</a> by a no less bizarre technique called &#8216;quantum simulation&#8217;, where hitting trapped ions with fine-tuned lasers makes them behave as free particles moving at fast speeds or as other types of quantum systems that are being simulated.</p>
<p>Speaking of the bizarre, biology was rich in that last month (when isn&#8217;t it?). Researchers attempted to tag some tree frogs with radio transmitters and learned something really weird: Tree frogs are apparently able to <a href="http://www.nature.com/news/2010/100105/full/news.2009.1170.html">move into the bladder and urinate</a> anything that was lodged in their body cavities: thorns, insects, radio transmitters. Also, a parasite was found, appropriately named <i>Endaphis fugitiva</i>, <a href="http://rspb.royalsocietypublishing.org/content/early/2010/01/12/rspb.2009.2029.abstract">which jumps out</a> of the banana aphid in which it lives when it realizes the aphid is in the jaws of a predator.</p>
<p>In promiscuous (but not in monogamous) mouse species, sperm cells can <a href="http://www.nature.com/nature/journal/vaop/ncurrent/abs/nature08736.html">recognize and team up with</a> sperm cells of the same male or, in a lesser extent, sperm of a brother. They form packs that swim faster than a single sperm cell. Also a couple researchers from Cincinnati decided to <a href="http://rspb.royalsocietypublishing.org/content/early/2010/01/05/rspb.2009.1720.full">circumsize fruit fly males with lasers</a> to see if their penis ornaments help them in mating.. Obviously, they do.</p>
<p>Speaking of sex, early last month a group from London made CNN news when they <a href="http://www3.interscience.wiley.com/journal/123232355/abstract">claimed that there is no G-spot</a> in human females, simply by asking a whole lot of twins if they think they have any, arguing against an earlier italian study where G-spot <a href="http://www3.interscience.wiley.com/journal/119425573/abstract">was actually located with ultrasound</a>.</p>
<p>And of course as everyone knows, paleontology had two major discoveries to hit the news: A polish group found <a href="http://www.nature.com/nature/journal/v463/n7277/abs/nature08623.html">well tetrapod tracks</a> in Middle Devonian, showing that tetrapods coexisted with elpistostegids (such as Tiktaalik) for over 10 million years in different niches. Some chinese paleontologists found melanosomes in fossil dinosaur feathers, suggesting that dino&#8217;s plumage was <a href="http://dx.doi.org/10.1038/nature08740">striped russet-orange and white</a>, overturning the idea that the color of prehistoric animals would never be known. How if they could find fossilized voice&#8230;</p>
<p>Something cool about humans: Ever seen movies where cowboys duel, the bad guy draws and the good guy reacts and draws faster? There&#8217;s truth to that: human brain <a href="http://rspb.royalsocietypublishing.org/content/early/2010/01/28/rspb.2009.2123.short?rss=1">reacts faster than acts</a> (by a small margin, and with more mistakes, but faster). Another curous find about us: barefoot running subjects humans to <a href="http://www.nature.com/nature/journal/v463/n7280/abs/nature08723.html">four times less stress</a> than shod running. Shoes make it easy to pick up the bad habit of landing on the heel.</p>
<p>And finally the poor little Mars explorer Spirit, stuck in a sand pit with two broken wheels since November, was finally declared a <a href="http://www.nature.com/news/2010/100129/full/463600a.html">&#8220;stationary research station&#8221;</a> (also covered by <a href="http://www.xkcd.com/695/">xkcd</a>).</p>
<p><small>Crossposted from <a href="http://cubbi.livejournal.com/72531.html">Livejournal</small></p>
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		<title>science review for december 2009</title>
		<link>http://drzubkov.com/2010/01/science-review-for-december-2009/</link>
		<comments>http://drzubkov.com/2010/01/science-review-for-december-2009/#comments</comments>
		<pubDate>Wed, 06 Jan 2010 16:02:56 +0000</pubDate>
		<dc:creator>cubbi</dc:creator>
				<category><![CDATA[science]]></category>

		<guid isPermaLink="false">http://drzubkov.com/?p=985</guid>
		<description><![CDATA[Now that I&#8217;ve sufficiently recovered from the New Year celebrations, let&#8217;s see what did the humanity learn in the past month. In chemistry, carbonic acid, H2CO3, was finally observed experimentally in solution. Speaking of simple targets, a teraherz study of water showed that dissolved ions neither weaken nor strengthen water&#8217;s structure, and yet another study [...]]]></description>
			<content:encoded><![CDATA[<p>Now that I&#8217;ve sufficiently recovered from the New Year celebrations, let&#8217;s see what did the humanity learn in the past month.</p>
<p>In chemistry, carbonic acid, H2CO3, was <a href="http://www.sciencemag.org/cgi/content/abstract/326/5960/1690">finally observed</a> experimentally in solution. Speaking of simple targets, a teraherz <a href="http://pubs.acs.org/doi/abs/10.1021/ja9083545">study of water</a> showed that dissolved ions neither weaken nor strengthen water&#8217;s structure, and <a href="http://pubs.acs.org/doi/abs/10.1021/ja907023c">yet another study</a> of caged water clusters showed how some can dry up and get rehydrated back. Another entertaining non-nano chemistry work, cyclooctatetraene <a href="http://pubs.acs.org/doi/abs/10.1021/ja908161r">was forcibly planarized</a> and the resulting antiaromatic molecule studied experimentally. Closer to my interests, solid-state NMR can now be used to determine <a href="http://pubs.acs.org/doi/abs/10.1021/ja906426p">structures of nontrivial proteins</a> and a new solution NMR sequence, <a href="http://pubs.acs.org/doi/abs/10.1021/ja909239w">HN(COCA)HAHB</a>, was developed to study unfolded proteins. Finally someone seriously cares about coupling constants in protein structure analysis.</p>
<p>In non-nano physics, mass of top quark <a href="http://link.aps.org/doi/10.1103/PhysRevD.80.092006">has been ascertained</a> to about 1% error. And in a rather groundbreaking quantum physics news, the 40 year old hypothesis of the universality of <a href="http://en.wikipedia.org/wiki/Vitaly_Efimov">Efimov trimers</a> has been experimentally <a href="http://www.sciencemag.org/cgi/content/abstract/326/5960/1683">shown to be true</a> last month by the <a href="http://www.media.rice.edu/media/NewsBot.asp?MODE=VIEW&#038;ID=13475">Hulet atom cooling lab in Rice U</a> (cute picture of a high-five from Efimov to Hulet there). The first Efimov trimer itself was only observed <a href="http://www.nature.com/nature/journal/v440/n7082/abs/nature04626.html">in 2006</a>, but this group confirmed the universality property and even observed Efimov tetramers.</p>
<p>In biology, <a href="http://rsif.royalsocietypublishing.org/content/early/2009/12/09/rsif.2009.0490.abstract">airflow inside dog&#8217;s nose was studied</a>: we now know that they smell with each nostril separately (like we hear sounds with each ear separately), and that they do not exhale scent when exhaling air. Microbiologists now know of <a href="http://www.pnas.org/content/106/51/21848.abstract">a new giant virus</a> from amoebae, although it doesn&#8217;t surpass <a href="http://en.wikipedia.org/wiki/Mimivirus">Mimivirus</a>. Another group, while studying rock-breathing bacteria, <a href="http://www.pnas.org/content/106/52/22169.abstract">figured out</a> how they create biological &#8220;wires&#8221; that pass through the cell wall and conduct electricity between the cell and the rock.</p>
<p>Psychology had a couple if interesting findings: a group of Swedish psychologists noticed that the <a href="http://www.pnas.org/content/106/51/21889.abstract">time it takes for a newborn mammal to walk</a> can be exactly calculated based on adult brain mass and gestation time, and that humans are not at all exceptional in their motor development. In more practical news, NYU psychologists demonstrated on human subjects that it&#8217;s possible <a href="http://www.nature.com/nature/journal/vaop/ncurrent/abs/nature08637.html">to completely erase fear</a> attached to a memory if it is modified at reconsolidation time, as was known to be possible in rats (if you didn&#8217;t know, after we recall any memory, there&#8217;s a moment a few minutes later when it is being reassembled to be put back in permanent storage, and it can be forever modified or even erased at that point). Speaking of memory, someone at Case Western studying short-term memory <a href="http://www.nature.com/neuro/journal/vaop/ncurrent/abs/nn.2458.html">managed to store information <i>in vitro</i></a>, in pieces of mammalian brain tissue.</p>
<p>Astronomers <a href="http://www.nature.com/nature/journal/v462/n7273/abs/nature08579.html">finally found an unambiguous example</a> of a <a href="http://en.wikipedia.org/wiki/Pair-instability_supernova">pair-instability supernova</a>, in another galaxy, naturally. In less distant news, Cassini was able to get a good look at <a href="http://photojournal.jpl.nasa.gov/catalog/PIA11682">the humongous planet-wide hexagonal cloud</a> on Saturn, first spotted back in the 1980s by Voyager.</p>
<p>And finally, in geology, the old and somewhat disputed <a href="http://en.wikipedia.org/wiki/Mantle_plume">deep mantle plume</a> hypothesis <a href="http://www.sciencemag.org/cgi/content/abstract/326/5958/1388">gained solid experimental support</a> with a new study of Hawaiian hot spot.</p>
<p>Also, in case you feel guilty about drinking champagne at New Year&#8217;s eve, <a href="http://journals.cambridge.org/action/displayAbstract?fromPage=online&#038;aid=6734272">it is just as good</a> at preventing cardiovascular disease as red wine <img src='http://drzubkov.com/wp-includes/images/smilies/icon_smile.gif' alt=':)' class='wp-smiley' /> </p>
<p>Almost forgot, last month&#8217;s animal behavior brought us the <a href="http://www.cell.com/current-biology/retrieve/pii/S0960982209019149">tool-using octopus</a> and the <a href="http://rspb.royalsocietypublishing.org/content/early/2009/12/18/rspb.2009.2139.full">explosive duck erections</a>!</p>
<p><small>Crossposted from <a href="http://cubbi.livejournal.com/72098.html">LiveJournal</a></small></p>
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